Treatment of warning lesion and pressure ulcer stage 1. ULCILENE is an oily solution, lubricating and protective, OGT base. Clinical studies carried out with ULCILENE have demonstrated that the product restores the epidermal lipid film of the skin, limits the insensitive water loss, facilitates the underlying tissue perfusion which help the natural healing process of injured zones of skin. A gentle massage with finger tip weight is sufficient.

Clinical studies (first)

Study title

Multicenter study of the efficacy of PB17 in prevention of decubitus ulcer in comparison with the classical techniques: 3 to 5 massages and dermo-epidermal kneading per day, with or without application of massage products.

Investigators

Dr Jean Rigal, Ex-Head of E.E.G. Department and Neurophysiology, Val-de-Grâce, Paris - France

Study Design

Open, multicentric – 137 patients. This study is part of the CE marking.

Study procedure

PB 17 was applied twice a day by gentle massage without deep kneading.

Results/Conclusions

In all studies conducted, patients and nursing staff agreed on the comfort and ease of use of the product compared to traditional treatments. In every case observed, the lesions were improved and the great majority were cured.

Clinical studies (second)

Study title

In vivo evaluation of the effect of an OGT solution on the renewal of the epidermis and on biomechanical skin properties in man.

Investigators

Laboratoires Dermscan, Lyon - France

Study Design

Open, one centre – 19 patients. This study is part of the CE marking.

Study procedure

2 applications twice a day by gentle massage of 1 minute

Results/Conclusions

Biomechanical properties of the skin: the firmness of the skin increased significantly (p<0.05) in the treated zone after two weeks of treatment Turnover of the epidermis: 100% turnover of the cells of the epidermis was obtained after 12±1days in the zone treated with Sanyrene versus 15±0 for the non treated zone. The difference was highly significant (p=0.0001)

Clinical studies (third)

Study title

Measurement of TcpO² at pressure points after application of on OGT solution

Investigators

D. Colin, D. Chomard, C. Bois, C. Bregeon, J.L. Saumet, University Hospital Centre, Angers - France

Study Design

Open, comparative – 28 patients. This study is part of the CE marking. This study is part of the CE marking.

Study procedure

Measurement were taken using a monitor (Microgas 7640, Kontron instruments) which provides a direct reading of TcpO² expressed in mm of Hg.

Results/Conclusions

The OGT solution decreased the negative effects of pressure exertion on skin microcirculation in the sacral area.

PUBLICATION

Article

Etude de l’efficacité de Sanyrène® après application locale unique sur la TcpO² de la région du sacrum chez des patients présentant un risque d’escarre.

Authors

Dr Colin, Dr Chomard : UCH Angers – France

Journal

La Revue de l’Infirmière N° 5 – Mars 1995